Aortic stiffness, measured invasively, or estimated from radial waveforms, predicts severe cardiovascular events
نویسندگان
چکیده
منابع مشابه
Elevated aortic pulse wave velocity, a marker of arterial stiffness, predicts cardiovascular events in well-functioning older adults.
BACKGROUND Aging results in vascular stiffening and an increase in the velocity of the pressure wave as it travels down the aorta. Increased aortic pulse wave velocity (aPWV) has been associated with mortality in clinical but not general populations. The objective of this investigation was to determine whether aPWV is associated with total and cardiovascular (CV) mortality and CV events in a co...
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Aortic systolic blood pressure (BP) represents the hemodynamic cardiac and cerebral burden more directly than office systolic BP. Whether invasively measured aortic systolic BP confers additional prognostic value beyond office BP remains debated. In this study, office systolic BP and invasively measured aortic systolic BP were recorded in 21 908 patients (mean age: 63 years; 58% men; 14% with d...
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Erectile dysfunction confers an independent risk for cardiovascular events and total mortality. Aortic pulse wave velocity (PWV) is an important predictor of cardiovascular events and all-cause mortality. We investigated whether PWV predicts major adverse cardiovascular events (MACEs) in patients with erectile dysfunction beyond traditional risk factors. MACEs in relation to PWV were analyzed w...
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Indicators of vascular dysfunction have emerged as surrogate markers for cardiovascular disease (CVD) progression and disease event prediction. Brachial artery flow-mediated dilation (FMD) evaluates conduit artery endothelial function and has been shown to predict incident CVD, particularly in individuals who are at high risk. Recently, the hyperemic response to ischemia has emerged as a key no...
متن کاملMicrovascular Function Contributes to the Relation Between Aortic Stiffness and Cardiovascular Events: The Framingham Heart Study.
BACKGROUND Arterial dysfunction contributes to cardiovascular disease (CVD) progression and clinical events. Inter-relations of aortic stiffness and vasodilator function with incident CVD remain incompletely studied. METHODS AND RESULTS We used proportional hazards models to relate individual measures of vascular function to incident CVD in 4547 participants (mean age, 51±11 years; 54% women)...
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ژورنال
عنوان ژورنال: European Heart Journal
سال: 2013
ISSN: 0195-668X,1522-9645
DOI: 10.1093/eurheartj/eht309.2892